Triple distillation was once quite common in Lowland distilleries, many of which distilled grains other than malted barley in pot stills, a practice that added delicacy and body to the whisky. Auchentoshan and Annandale are the only remaining Lowland distilleries that employ triple distillation, and before 2014, they were among only four malt whisky distilleries remaining in the Lowlands. Auchentoshan was founded in 1817 by corn merchant John Bulloch (then called Duntocher), but he filed for bankruptcy in 1822. His son Archibald obtained a distillation license under the 1823 Act, but also faced bankruptcy in 1826. In 1834, Duntocher was sold to John Hart and Alexander Filshie of Bulloch & Co.—the latter a local farmer whose family had lived in the area since the 17th century—on the condition that John Bulloch could continue living at the distillery (he died in 1846 at age 87). John Hart and Alexander Filshie renamed the distillery Auchintoshan (misspelled), meaning 'corner of the field.' The Filshie family owned the distillery for 44 years. They rebuilt it in 1875, but after a disastrous grain harvest in 1877, sold it to the Greenock whisky merchants C.H. Curtis & Company. C.H. Curtis & Company operated Auchentoshan until 1900. Over the next three years, the distillery changed hands twice, the second time being sold to John and George McLachlan Ltd., a company combining brewer, distiller, and wine/spirits merchant. In 1960, it was acquired by the brewer Tennent. Tennent merged with Charrington in 1964 (later becoming Bass Charrington), and in 1969 the distillery was sold to Eadie Cairns for approximately £100,000. They renovated the plant, installed new equipment, and sold it to its current owner, Suntory, in 1984. The Japanese brewing and distilling company Suntory acquired Morrison Bowmore in 1994, and in 2015 Suntory merged with Jim Beam.

Auchentoshan is located just 20 minutes west of Glasgow, and its prime location makes it a popular tourist destination. The distillery renovated some facilities in 2004 and 2008 to enhance the visitor experience (Scottish Tourist Board 5-star attraction certification). All of its output is bottled as a single malt whisky and marketed as 'Glasgow's Malt Whisky.' The Bulloch family has continued to play a significant role in the whisky industry. Bulloch Company was established in 1830 and was sold to D. T. Campbell shortly after. In 1855, John Bulloch's grandson led a merger with the successful Glasgow whisky firm A. Lade & Company to form Bulloch Lade & Company, and continued acquiring: Camlachie/Loch Katrine in 1856, Caol Ila in 1863, and Benmore in Campbeltown in 1868. The company also sold a series of renowned blended whiskies under the 'B.L.' brand name, and until 1893, it was the exclusive agent for the Macallan-Glenlivet distillery. In 1898, Bulloch Lade was further corporatized and joined D.C.L. in 1920. The distillery's three-stage distillation process is as follows: The wash is fed into the wash still, and the low wines extracted are sent to the No. 1 spent lees receiver, where they are mixed with the tails from the intermediate still (alcohol strength approximately 18%-19%). The liquid from the No. 1 spent lees receiver is fed into the smaller intermediate still for distillation, and the heads obtained are sent to the No. 2 spent lees receiver, where they are mixed with the tails from the spirit still (alcohol strength approximately 55%). The liquid from the No. 2 spent lees receiver is then fed into the spirit still and distilled in the usual manner; the heads and tails are returned to the No. 2 spent lees receiver, while the heart is saved in the spirit receiver. The overall alcohol strength is extremely high, reaching 82%. In 2008, the distillery made major renovations to its packaging and liquid. Since the competition began in 2003, Three Wood has entered the finals of the Cuban Whisky and Rum Challenge every year and won in 2005 (paired with Bolivar Inmensas cigars).