Moffat (named after a former mill on the site) is located in the suburbs of Airdrie, comprising 30 high-quality maturation warehouses (approximately 480,000 oak casks), a bottling plant, and offices. The distillery itself was demolished in the 1980s. The reasons for choosing this location were excellent water supply, sufficient labor, and a central geographic position, plus a good transportation network. There was once a paper mill here, which had been closed for about three years when Inver House acquired this somewhat derelict site. Inver House was then a subsidiary of Publicker Industries Inc., intending to produce both malt and grain whisky at the same location, primarily to meet the demand for Inver House Green Plaid in the US market. Renovation of the old mill began in spring 1964, with the first malt whisky distillation starting in February 1965, and the first grain whisky produced a month later. The distillery's three stills produced three malt whiskies with different styles and peat content (unpeated Killyloch, lightly peated Glenflagler, and heavily peated Islebrae). Islebrae was initially named Glen Moffat. The grain whisky produced at Moffat distillery was named Garnheath. In 1982, malt whisky distillation ceased, and grain whisky distillation stopped in 1986. In 1988, Inver House was bought by a management team led by Bill Roden for £8.2 million from its American owners. The company had lost £2.12 million the previous year, with cumulative losses reaching £9.7 million. Since then, the company has achieved remarkable success, and in 2001 the directors sold it to Thailand's Pacific Spirits for £56 million.

The scale of the Moffat Distilling Centre at the time of its construction allowed it to have its own malting equipment, and shortly after the investment, a Wanderhaufen box malting system (the famous 'moving street') was installed—starting with 1 'street' and eventually developing into 7, processing up to 700 tons of barley daily, and equipped with 4 kilns. This was the largest malting plant in Europe at the time. The malting plant closed in 1978. During its peak in the 1970s, the Moffat Distilling Centre employed nearly 1,000 people. The grain whisky produced here was never bottled separately. Four types of malt whisky appeared on the market, but they were extremely rare, mainly products from independent bottlers. Glenflagler was bottled by Inverhouse in the mid-1980s, releasing 5-year and 8-year products.